Multidisciplinary management of hepatobiliary tumors in the era of precision medicine
Jian-Zhen Lin a, Yi Bai a, An-Qiang Wang b, Jun-Yu Long a, Wei-Yu Xu a, Ke Hu c, Lin Zhao d, Jie Pan e, Xin-Ting Sang a, Hai-Tao Zhao a,*
a Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China b Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing 100142, China c Center of Radiotherapy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China d Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China e Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
*Corresponding author.
E-mail address: zhaoht@pumch.cn (H.-T. Zhao)
Abstract：Hepatobiliary tumor (HBT), one of the leading causes of cancer deaths globally, is more frequent in East Asia including China [1] . HBT includes liver cancer, cholangiocarcinoma and gallbladder cancer. HBT burden varies markedly by gender and geographic region due to the exposure of risk factors. Majority of the hepatocellular carcinomas are associated with hepatitis B-type virus infection [2] , and approximate 70% patients were male in China. Other risk factors include infections (hepatitis C virus), aflatoxins, flukes in endemic areas, behavioral factors (alcohol, tobacco), metabolic factors (diabetes, obesity) and congenital disease (bile duct cyst). The pathogenesis of HBTs are complex and HBTs possess high-level tumor heterogeneity (both intra- and inter-tumor) [3,4] , it is important to conduct a comprehensive assessment for every patient before making decision in treatment, which needs multidisciplinary management efforts.
. [J]. Hepatobiliary Pancreat Dis Int, 2018, 17(5): 381-382.
Lin JZ, Bai Y, Wang AQ, Long JY, Xu WY, Hu K, Zhao L, Pan J, Sang XT, Zhao HT. Multidisciplinary management of hepatobiliary tumors in the era of precision medicine. Hepatobiliary Pancreat Dis Int, 2018, 17(5): 381-382.
2018, Vol. 17 
