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Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice |
Chao Fan, Xiao-Peng Yan, Shi-Qi Liu, Chun-Bao Wang, Jian-Hui Li, Liang Yu, Zheng Wu and Yi Lv |
Xi an, China
Author Affiliations: Department of Hepatobiliary Surgery (Fan C, Yan XP, Liu SQ, Yu L, Wu Z and Lv Y) and Department of Pathology (Wang CB), First Affiliated Hospital, School of Medicine, Xi an Jiaotong University, Xi an 710061, China; Department of Surgical Oncology, Third Affiliated Hospital, School of Medicine, Xi an Jiaotong University (Shaanxi Provincial People s Hospital), Xi an 710068, China (Li JH)
Corresponding Author: Yi Lv, MD, Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi an Jiaotong University, Xi an 710061, China (Tel: 86-29-85323904; Email: luyi169@126.com) |
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Abstract BACKGROUND: The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications has remained high. A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.
METHODS: After ligating the common bile duct for 7 days, 16 dogs were randomly divided into two groups (n=8 per group). Anastomats were used in the study group, and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy. We compared the operation time, incidence of complications, gross appearance, and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.
RESULTS: The time spent on constructing the anastomosis for the study group was significantly shortened. Although no anastomotic stenosis occurred in the two groups, the narrowing rate of biliary-enteric anastomosis was much higher in the control group. There was one case of bile leakage in the control group, whereas no bile leakage occurred in the study group. A smoother surface, an improved layer apposition, and a lower local inflammatory response were identified in the anastomosis of the study group.
CONCLUSION: The structures of the novel magnetic compressive anastomats are simple, and they are time-saving, safe and efficient for performing Roux-en-Y choledochojejunostomy procedures in a canine model of obstructive jaundice.
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