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Xanthogranulomatous pancreatitis treated by duodenum-preserving pancreatic head resection |
Alper Uguz, Sava? Yakan, Baris Gurcu, Funda Yilmaz, Tankut Ilter and Ahmet Coker |
Izmir, Turkey
Author Affiliations: Department of Surgery, Hepatopancreatobiliary Division (Uguz A, Yakan S, Gurcu B and Coker A); Department of Pathology (Yilmaz F); and Department of Gastroenterology (Ilter T), Ege University Faculty of Medicine, Izmir, Turkey
Corresponding Author: Sava? Yakan, 255 sokak No: 1/7 35270 Hatay Izmir, Turkey (Tel: +90-533-471-7940; Fax: +90-232-261-4444; Email: savasyakan@gmail.com) |
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Abstract BACKGROUND: Xanthogranulomatosis is an idiopathic, rare process in which lipid-laden histiocytes are deposited at various locations in the body. We present two cases who were treated by duodenum-preserving pancreatic head resection and eventually diagnosed as having xanthogranulomatous pancreatitis.
METHODS: A 30-year-old caucasian man was admitted to our clinic for vague abdominal pain and epigastric dullness. Magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography suggested the existence of chronic pancreatitis. Another 34-year-old caucasian woman was admitted to our clinic because of right upper quadrant pain. Magnetic resonance cholangiopancreatography demonstrated a dilatation and stone of the main pancreatic duct. Based on a diagnosis of chronic pancreatitis, pancreatic head resection was planned and a laparotomy was performed in both of cases.
RESULTS: In both cases, duodenum-preserving pancreatic head resection was performed. Macroscopic and microscopic findings revealed xanthogranulomatous inflammation, which led to a diagnosis of xanthogranulomatous pancreatitis.
CONCLUSION: Although this type of pancreatitis is extremely rare, it is important to keep it in mind for a differential diagnosis because it may simulate chronic pancreatitis or a malignant tumor on imaging.
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