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Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma |
Mirko Muroni, Francesco DAngelo, Massimo Pezzatini, Simone Sebastiani, Samantha Noto, Emanuela Pilozzi and Giovanni Ramacciato |
Rome, Italy
Author Affiliations: Department of General Surgery (Muroni M, DAngelo F, Pezzatini M, Sebastiani S and Ramacciato G), and Department of Pathology (Noto S and Pilozzi E), La Sapienza University of Rome, Second School of Medicine, St. Andrea Hospital, via di Grottarossa 1035, 00189 Rome, Italy
Corresponding Author: Mirko Muroni, MD, Department of General Surgery, La Sapienza University of Rome, St. Andrea Hospital, viale Gino Cervi 53 L, 00139, Rome, Italy (Fax: 0039-06-33775322; Email: mirkomuroni@libero.it). |
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Abstract BACKGROUND: The association between gastric and pancreatic carcinoma is a relatively rare condition. In gastric carcinoma patients, the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics. Gastric cancer associated with pancreatic cancer is uncommon.
METHODS: We report a case of a 73-year-old patient hospitalized for vomiting and weight loss. Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum. Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3×1.7 cm) in the uncinate portion of the pancreas.
RESULTS: The patient underwent pancreaticoduodenectomy according to Whipple regional type Ⅰ Fortner. Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.
CONCLUSIONS: Long survival is rare in patients with associated gastric and pancreatic cancer. Surgical resection remains the only potentially curative treatment.
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