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Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia: report of a case |
Rajkumar Krishnasamy, Shaleen Agarwal, Shivendra Singh, Sunil Puri, Puja Sakhuja and Anil K Agarwal |
New Delhi, India
Author Affiliations: Department of Gastrointestinal Surgery (Krishnasamy R, Agarwal S, Singh S and Agarwal AK), Department of Radiology (Puri S), and Department of Pathology (Sakhuja P), Govind Ballabh Pant Hospital and Maulana Azad Medical College (Delhi University), New Delhi 110002, India
Corresponding Author: Anil K Agarwal, MD, Department of Gastrointestinal Surgery, Govind Ballabh Pant Hospital and Maulana Azad Medical College (Delhi University), New Delhi 110002, India (Tel: 91-11-23235702; Fax: 91-11-23235702; Email: aka.gis@gmail.com) |
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Abstract BACKGROUND: The presence of pancreatic ductal intraepithelial neoplasia in patients with chronic pancreatitis is a risk factor for development of pancreatic adenocarcinoma.
METHOD: A case of pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia was diagnosed in the setting of chronic pancreatitis.
RESULTS: Distal pancreatectomy combined with splenec-tomy was performed with a diagnosis of pancreatic body carcinoma. Histopathological examination suggested adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia. The tumor was detected in the remaining head of the pancreas, for which a total pancreatectomy was done.
CONCLUSIONS: When a patient with pancreatic ductal intraepithelial neoplasia associated with adenocarcinoma of the pancreas in the setting of chronic pancreatitis is at an increased risk of recurrence in the remaining pancreatic parenchyma, total pancreatectomy may be feasible.
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Cite this article: |
Krishnasamy R,
Agarwal S,
Singh S,
et al.
Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia: report of a case.
Hepatobiliary Pancreat Dis Int
2007;
6(5):
553-556. DOI:
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URL: |
http://dx.doi.org/ OR http://www.hbpdint.com/EN/Y2007/V6/I5/553 |
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