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| Clinical manifestations of patients with chronic pancreatitis |
| Wei-Xing Chen, Wei-Fang Zhang, Bo Li, Hui-Jia Lin, Xian Zhang, Hong-Tan Chen, Zhu-Ying Gu and You-Ming Li |
Hangzhou, China
Author Affiliations: Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Chen WX, Li B, Lin HJ, Zhang X, Chen HT, Gu ZY and Li YM); Department of Intensive Care Unit, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Zhang WF)
Corresponding Author: Wei-Xing Chen, MD, PhD, Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Tel: 86-571-88382089; Email:chenweixing@hotmail.com) |
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Abstract BACKGROUND: Recent advances in molecular and genomic technologies and pancreatic imaging techniques provided some insights into genetic, environmental, immunologic, and pathobiological factors for chronic pancreatitis (CP). This study was undertaken to investigate the clinical manifestations of patients with chronic pancreatitis at our hospital.
METHODS: The data of the patients with CP who had been treated at our hospital between 1997 and 2004 were analyzed.
RESULTS: The major symptoms of the patients with CP were abdominal pain, dyspepsia, loss of weight, diabetes mellitus, pancreatic pseudocyst, steatorrhea, and calcification. Biliary diseases were found to be the first cause of CP in this study; but alcohol abuse was the major cause of CP in men and biliary diseases were the first etiological factors for CP in women. The etiological difference of constituent ratio between men and women was related to alcohol comsumption (P<0.01).
CONCLUSIONS: During the past 8 years, biliary diseases have been the major etiological factors for CP, but their constituent ratio is decreasing, and the constituent ratio of alcohol abuse is increasing gradually. Alcohol tends to replace biliary diseases as the primary etiological factor for CP.
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2006, Vol. 5 
