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| Detection of anti-MHAV and anti-MHEV IgM in patients with sporadic acute hepatitis in Beijing between 1995-2000 |
| Jian Lu, Hong-Lan Zhao, Qing-Ling Meng, Sheng-Dong Liao, Yuan Wang and Yong-Zhen Jiang |
From the Laboratory of Hepatitis, institute of Virology, Chinese Academy of preventive Medicine, Beijing 100052, China (Lu J, Zhao HL, Meng QL, Liao SD, Wang Y and JIang YZ)
Correspondence: Jian Lu, MD (Tel: 86-10-63581359; Fax: 86-10-63532053; Email: jlu@btamial.net.cn) |
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Abstract Objective: To investigate the age range, liver function damage and prognosis of patients with sporadic acute hepatitis A and E in Beijing.
Methods: Enzyme immunoassay (EIA) was used to detect anti-HAV and anti-HEV immunoglobulin M (IgM). Serum samples were collected from the patients with sporadic acute viral hepatitis in Beijing from January 1995 to June 2000.
Results: The total Positive rate for anti-HAV and anti-HEV IgM was 55.2% (112) in 203 patients with acute hepatitis, of whom 22.2% (45 patients) and 33.0% (67) were positive for anti-HAV and anti-HEV respectively. The duration of anti-HEV IgM was 45-60 days and that of anti-HAV IgM was at least 2-3 months. The patients with acute hepatitis A and hepatitis E all experienced jaundice and a rising of liver enzyme, but did not develop chronic hepatitis or died.
Conclusion: Acute hepatitis A as well as acute hepatitis E plays an important role in sporadic enterically transmitted hepatitis in Beijing.
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2002, Vol. 1 
