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| Kidney transplantation after liver transplantation |
| Li-Yang Wu, Hang Liu, Wei Liu, Han Li and Xiao-Dong Zhang |
Beijing, China
Author Affiliations: Department of Urology (Wu LY, Liu H and Zhang XD), Department of Surgical Intensive Care Unit (Liu W), and Department of Blood Purification (Li H), Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
Corresponding Author: Xiao-Dong Zhang, MD, PhD, Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China (Tel/Fax: +86-10-85231383; Email: zhangxiaodong@bjcyh.com) |
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Abstract Kidney transplantation after liver transplantation (KALT) offers longer survival and a better quality of life to liver transplantation recipients who develop chronic renal failure. This article aimed to discuss the efficacy and safety of KALT compared with other treatments. The medical records of 5 patients who had undergone KALT were retrospectively studied, together with a literature review of studies. Three of them developed chronic renal failure after liver transplantation because of calcineurin inhibitor (CNI)-induced nephrotoxicity, while the others had lupus nephritis or non-CNI drug-induced nephrotoxicity. No mortality was observed in the 5 patients. Three KALT cases showed good prognoses, maintaining a normal serum creatinine level during entire follow-up period. Chronic rejection occurred in the other two patients, and a kidney graft was removed from one of them. Our data suggested that KALT is a good alternative to dialysis for liver transplantation recipients. The cases also indicate that KALT can be performed with good long-term survival.
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2016, Vol. 15 
