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| Detecting chimerism contributes to diagnosis of graft versus host disease after orthotopic liver transplantation |
| Bo Peng, Hong Liu, Quan Zhuang, Ke Cheng, Ying-Zi Ming ∗ |
Transplantation Center of the Third Xiangya Hospital, Central South University, Changsha 410013, China Engineering & Technology Research Center for Transplantation Medicine of National Ministry of Health, Changsha 410013, China
∗Corresponding author.
E-mail address: myz_china@aliyun.com (Y.-Z. Ming) |
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Abstract Graft versus host disease (GVHD) occurs when the immuno- competent cells from the donor mount an immune response against the tissues of the host [1] . It is commonly seen in the patients who received hematopoietic stem cell transplantation (HSCT). GVHD is a rare but lethal complication in orthotopic liver transplantation (OLT). The incidence varies from 0.1% to 2.0%, while the mortality rate is up to 75.0% [2 –4] . Herein, we reported a successfully treated case of GVHD after OLT, who was diagnosed timely with the help of a novel chimerism test technique, and was treated with drug withdraw and basiliximab.
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2018, Vol. 17 
