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| Primary pancreatic gastrointestinal stromal tumor |
| Whayoung Lee a , Xiaodong Li a , Sonia Lee b , Vishal S Chandan a , ∗ |
a Department of Pathology and Laboratory Medicine, University of California, Irvine, CA 92868, USA
b Department of Radiological Sciences, University of California, Irvine, CA 92868, USA
∗ Corresponding author.
E-mail address: vchandan@hs.uci.edu (V.S. Chandan). |
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Abstract Gastrointestinal stromal tumor (GIST) arises from the interstitial cells of Cajal (ICC) and is the most common mesenchymal tumor of the gastrointestinal tract, accounting for approximately 1%-2% of all malignant gastrointestinal tract tumors [1]. The most common sites of origin are stomach and small bowel. Rarely extra-gastrointestinal GISTs are reported originating from omentum, mesentery and retroperitoneum [2,3]. Primary pancreatic GIST is exceedingly rare with only approximately 50 reported cases [4–7]. The reported age for patients with primary pancreatic GIST ranges from 30 to 84 years, without sex predilection. The common clinical manifestations include dull abdominal pain, abdominal mass, bleeding/anemia and weight loss; however, some cases are diagnosed incidentally [4,8]. Here, we report a very rare case of primary pancreatic GIST presenting as a 6 cm solid mass with cystic component in the pancreatic head region.
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2021, Vol. 20 
