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Successful adult-to-pediatric liver transplantation of discarded partial liver allograft with benign caudate lobe tumor |
Jia-Hao Pei # , Cong-Huan Shen # , Rui-Dong Li # , Yi-Feng Tao, Lu Lu, Zheng-Xin Wang ∗ |
Department of General Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China
∗ Corresponding author.
E-mail address: wangzhengxin@huashan.org.cn (Z.-X. Wang) .
# Contributed equally. |
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Abstract Pediatric liver transplantation is the only treatment option for end-stage liver disease in children, and the 5-year and 20-year survival rates after living donor liver transplantation (LDLT) can reach 91.5% and 84.2% [1]. Many Asian countries, including China, have begun to develop LDLT and achieved good progress. However, the shortage of donor livers in children remains a serious problem. Parents with hepatitis B virus, fatty liver, or blood type incompatibility, and those with strong ethical objections are not suitable donors, and many children have to wait for a suitable liver source. We recently have used five split discarded left lateral lobe as donor liver from living patients with caudate lobe benign tumors and have achieved good results. Here, we share our experiences of using discarded liver grafts as donor liver in pediatric liver transplantation. Both the hepatectomy and “discarded” graft procurement surgery were approved by the Medical Affairs Department and the Ethics Committee of the Huashan Hospital of Fudan University.
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