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Implementation of gastrointestinal function protection in severe acute pancreatitis |
Fu-Zheng Tao a , Rong-Lin Jiang b , Shui-Fang Jin b , ∗ |
a Intensive Care Unit, Taizhou Integrated Traditional Chinese and Western Medicine Hospital, Taizhou 310075, China
b Intensive Care Unit, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou
310006, China
∗ Corresponding author.
E-mail address: jinsf-810620@163.com (S.-F. Jin). |
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Abstract Severe acute pancreatitis (SAP) is a serious systemic disease associated with strong local inflammatory reactions and serious systemic pathophysiological disorders caused by trypsin spillover. Patients with SAP are prone to exhibit gastrointestinal dysfunction. Meanwhile, gastrointestinal dysfunction further aggravates the systemic inflammatory response and metabolic abnormalities, resulting in a more critical condition of SAP. Gastrointestinal dysfunction is considered to be the “trigger” of multiple organ dysfunction syndrome [1]. Thus, it is important to maintain gastrointestinal homeostasis in the treatment of SAP.
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