Chinese expert consensus on organ protection of transplantation (2022 edition)
Jian-Hui Li a , Xiao Xu b , Yan-Feng Wang c , Hai-Yang Xie d , Jing-Yu Chen e , Nian-Guo Dong f , Mitesh Badiwala g , Li-Ming Xin h , Roberto Vanin Pinto Ribeiro g , Hao Yin i , Hao Zhang j , k , Jian-Zheng Zhang j , k , Feng Huo l , Jia-Yin Yang m , Hong-Ji Yang n , Hui Pan o , Shao-Guang Li j , k , Yin-Biao Qiao d , Jia Luo d , Hao-Yu Li d , Jun-Jun Jia p , Hao Yu p , Han Liang c , Si-Jia Yang o , Hao Wang j , k , Zhong-Yang Liu j , k , Li-Cheng Zhang j , k , Xiao-Yi Hu p , Hao Wu p , Yi-Qing Hu p , Pei-Fu Tang j , k , Qi-Fa Ye c , Shu-Sen Zheng a , d , p , ∗
a Department of Hepatobiliary and Pancreatic Surgery, Department of Liver Transplantation, Shulan (Hangzhou) Hospital, Zhejiang Shuren University School
of Medicine, Hangzhou 310022, China
b Department of Hepatobiliary and Pancreatic Surgery, Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China
c Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key
Laboratory of Medical Technology on Transplantation, Wuhan 430062, China
d NHC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou 310003, China
e Wuxi Lung Transplantation Center, Wuxi People’s Hospital Affiliated with Nanjing Medical University, Wuxi 214023, China
f Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
g Peter Munk Cardiac Centre, Toronto General Hospital-University Health Network, Toronto, Canada
h School of Computer Engineering and Science, Shanghai University, Shanghai 200444, China
i Organ Transplant Center, Shanghai Changzheng Hospital, Shanghai 200003, China
j Department of Orthopedics, Chinese PLA General Hospital, Beijing 100039, China
k National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation, Beijing 100039, China
l Department of Surgery, General Hospital of Guangzhou Military Command of PLA, Guangzhou 510040, China
m Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu 610041, China
n Organ Transplantation Center, Sichuan Provincial People’s Hospital and School of Medicine, University of Electronic Science and Technology of China,
Chengdu 610072, China
o Department of Lung Transplantation, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
p Division of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
∗ Corresponding author at: Department of Hepatobiliary and Pancreatic Surgery, Department of Liver Transplantation, Shulan (Hangzhou) Hospital, Zhejiang Shuren University School of Medicine, Hangzhou 310022, China.
E-mail address: shusenzheng@zju.edu.cn (S.-S. Zheng) .
Abstract:Organ transplantation increases survival and improves quality of life to many patients with end-stage organ failure. Organ shortage is a worldwide problem that restricts organ transplantation [1]. Organ procurement and preservation as well as ischemia-reperfusion injury (IRI) after transplantation are the important factors affecting prognosis of recipients. Since the development of organ transplantation technology in the 20th century, organ protection technology has been a most promising concept in this field. Organ preservation solutions such as the Collins solution, University of Wisconsin (UW) solution, and histidinetryptophan- ketoglutarate (HTK) solution were developed sequentially [2], which developed rapidly in static cold storage (SCS) techniques. SCS remains the standard preservation technique for organ transplantation [2], but it invariably leads to a progressive decline in organ viability and function. It also precludes dynamic assessment of organ function to determine the adequacy for transplantation.
引用本文:
. [J]. Hepatobiliary Pancreat Dis Int, 2022, 21(6): 516-526.
Li JH, Xu X, Wang YF, Xie HY, Chen JY, Dong NG, Badiwala M, Xin LM, Ribeiro RVP, Yin H, Zhang H, Zhang JZ, Huo F, Yang JY, Yang HJ, Pan H, Li SG, Qiao YB, Luo J, Tang PF, Ye QF, Zheng SS. Chinese expert consensus on organ protection of transplantation (2022 edition). Hepatobiliary Pancreat Dis Int, 2022, 21(6): 516-526.