Liver transplantation and liver resection as alternative treatments for primary hepatobiliary and secondary liver tumors: Competitors or allies?
Jan Lerut
Institute for Experimental and Clinical Research (IREC), Université catholique Louvain (UCL), Avenue Hippocrate 56, 1200 Woluwe Saint Pierre, Brussels,
Belgium
Abstract：Although Starzl designed in the 1960’s liver transplantation (LT) to treat unresectable primary and also secondary liver tumors, transplantation still occupies a (too) small place in the respective therapeutic algorithms [1] . Due to the lack of (any) selection criteria, the concept of transplantation became rapidly challenged because of the prohibitively high incidence of tumor recurrence [1–3] . Not surprisingly, the “oncological pendulum” reversed in the nineties and moved the indication for LT from large multifocal lesions to a more limited tumor burden. In fact the paradigm changed towards transplanting the resectable and resecting the “untransplantable” cancer [4] . More recently the pendulum is going again in the opposite direction based on major progresses made in the medico-surgical treatment of these different tumors [5–14] . Seen the great potential of LT in the treatment of liver tumors, our team introduced in 2015 in the medical literature the term “transplant oncology” in clinical practice [15] .
引用本文:
. [J]. Hepatobiliary Pancreat Dis Int, 2024, 23(2): 111-116.
Lerut J. Liver transplantation and liver resection as alternative treatments for primary hepatobiliary and secondary liver tumors: Competitors or allies?. Hepatobiliary Pancreat Dis Int, 2024, 23(2): 111-116.
2024, Vol. 23 
