Robotic versus laparoscopic surgery for sporadic benign insulinoma: Short- and long-term outcomes
Zhu-Zeng Yin a , # , Yuan-Xing Gao a , # , Zhi-Ming Zhao a , Ming-Gen Hu a , Wen-Bo Tang a , Rong Liu a , b , c , ∗
a Faculty of Hepato-Pancreato-Biliary Surgery, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
b Institute of Hepatobiliary Surgery of Chinese PLA, Beijing 100853, China
c Key Laboratory of Digital Hepatobiliary Surgery of Chinese PLA, Beijing 100853, China
∗Corresponding author at: Faculty of Hepato-Pancreato-Biliary Surgery, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
E-mail address: liurong301@126.com (R. Liu).
# Contributed equally.
Abstract：Background: Minimally invasive surgery is the optimal treatment for insulinoma. The present study aimed to compare short- and long-term outcomes of laparoscopic and robotic surgery for sporadic benign insulinoma.
Methods: A retrospective analysis of patients who underwent laparoscopic or robotic surgery for in- sulinoma at our center between September 2007 and December 2019 was conducted. The demographic, perioperative and postoperative follow-up results were compared between the laparoscopic and robotic groups.
Results: A total of 85 patients were enrolled, including 36 with laparoscopic approach and 49 with robotic approach. Enucleation was the preferred surgical procedure. Fifty-nine patients (69.4%) underwent enucleation; among them, 26 and 33 patients underwent laparoscopic and robotic surgery, respectively. Robotic enucleation had a lower conversion rate to laparotomy (0 vs. 19.2%, P = 0.013), shorter operative time (102.0 vs. 145.5 min, P = 0.008) and shorter postoperative hospital stay (6.0 vs. 8.5 d, P = 0.002) than laparoscopic enucleation. There were no differences between the groups in terms of intraoperative blood loss, the rates of postoperative pancreatic fistula and complications. After a median follow-up of 65 months, two patients in the laparoscopic group developed a functional recurrence and none of the patients in the robotic group had a recurrence.
Conclusions: Robotic enucleation can reduce the conversion rate to laparotomy and shorten operative time, which might lead to a reduction in postoperative hospital stay.
2024, Vol. 23 
