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| Orthotopic liver transplantation in treatment of 77 patients with end-stage hepatic disease |
| Shu-Shen Zheng, Dong-Sheng Huang, Wei-Lin Wang, Ting-Bo Liang, Min Zhang, Yan Shen, Xiao Xu, Jian Wu, Sheng Yan, Hua Guo and An-Wei Lu |
From the Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Zheng SS, Huang DS, Wang WL, Liang TB, Zhang M, Shen Y, Xu X, Wu J, Yan S, Guo H and Lu AW)
Correspondence: Shu-Sen Zheng, MD, PhD (Tel: 86-571-87236570; Fax: 86-571-87236628; Email: linzhou8@mail.hz.zj.cn) |
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Abstract Objective: To summarize the experience of human orthotopic liver transplantation (OLTx) in treatment of patients with end-stage hepatic disease and their perioperative management.
Methods: A retrospective analysis was made on OLTx performed in 77 patients from April 1993 to September 2001 in our department included combined liver-Kidney transplantation (6 patients) and living related liver transplantation (2). Among them, 76 were adults and 1 was infant (67 males and 10 females). The donors included 75 non-heart beating donors and 2 living related donors. Veno-venous bypass was used only in 45 cases during the operation. immunosuppressive agents consisted of cyclosporine, cellcept, ALG corticosteroids and FK506.
Results: The one-year survival rates of grafts and recipients with benign hepatic disease were 75%. The recipients this year are surviving with good function of grafts.
Conclusion: liver transplantation is the best therapeutic method for a large number of patients with end-stage hepatic disease in China.
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2002, Vol. 1 
