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| Administration of tacrolimus in 50 liver transplantation patients |
| Qi-Fa Ye, Manal Abdel Ruzig and Nian-Qiao Gong |
From the Institute of Organ Transplantation and Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China (Ye QF, Ruzig MA and Gong NQ)
Correspondence: Qi-Fa Ye, MD (Tel: 86-27-83662668; Fax: 86-27-83798589; Email: yqf_china@sina.com) |
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Abstract Objective: To present a good tacrolimus (FK506) administration protocol in liver transplantation.
Methods: Fifty liver transplantation patients were classified into FK506 high-concentration (20 patients), FK506 mid-concentration (20), CsA-FK506 (5) and FK506-CsA (5) groups. Clinical manifestations, FK506 side-effects and pathological changes were observed.
Results: The FK506 high-concentration group showed complications such as infection and liver function damage. The FK506 mid-concentration group showed excellent therapeutic results and some complications easy to deal with.
Conclusion: FK506 is a highly effective immunosuppressive agent and the mid-concentration protocol is a better one.
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2002, Vol. 1 
