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NF-κB in allograft rejection |
Jian-Feng Wei and Shu-Sen Zheng |
Hangzhou, China
From the Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Wei JF and Zheng SS)
Correspondence: Jian-Feng Wei, PhD (Tel: 86-571-8723 6570; Email:doctorwjf@sohu.com)
ABSTRACT: Nuclear factor-kappa B (NF-κB) as an essential transcription factor in the control of expression of the cytokine-induced genes in immune and inflammatory responses regulates cytokines in allograft rejection. In this review, we summarize the general properties of NF-κB and the principal findings to shed new light on transplantation. |
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Abstract ABSTRACT: Nuclear factor-kappa B (NF-κB) as an essential transcription factor in the control of expression of the cytokine-induced genes in immune and inflammatory responses regulates cytokines in allograft rejection. In this review, we summarize the general properties of NF-κB and the principal findings to shed new light on transplantation.
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