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Interventional therapy of malignant obstructive jaundice |
Guang-Hua Feng, Yang Cai, Zhong Jia, De-Qi Yang, Hu Chen, Hui-Cheng Jin, Qiang-Hong Yu, Wei Zhu and Chu-Xiong Wang |
Hangzhou, China
From the Departments of General Surgery (Feng GH, Cai Y, Jia Z, Jin HC and Zhu W) and Radiology (Yang DQ, Chen H, Yu QH and Wang CX), First People’s Hospital, 261 Huansha Road, Hangzhou 310006, China
Correspondence: Guang-Hua Feng, MD (Tel: 86-571-87065701; Fax: 86-571-87914773; Email: caiyang68@hotmail.com) |
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Abstract OBJECTIVE: To assess the short-term results of interventional therapy for malignant obstructive jaundice.
METHODS: In 82 patients with malignant obstructive jaundice, hepatocellular carcinoma was detected in 10 patients, carcinoma of gallbladder in 14, hilar biliary carcinoma in 22, pancreatic carcinoma in 20, and hilar metastatic carcinoma in 16. Percutaneous transhepatic biliary internal and/or external drainage (PTBIED) was performed in 61 patients and percutaneous transhepatic insertion of biliary stent (PTIBS) in 21.
RESULTS: The level of total serum bilirubin (TSB) was reduced in 71 patients and less markedly in others. The level of TSB of the 61 patients was reduced from 450.12±113.51 μmol/L before operation to 240.25±107.81 μmol/L and 90.91±101.72 μmol/L 1 and 2 weeks after operation respectively. The TSB level of the 21 patients was reduced from 410.53±98.13 μmol/L to 270.23±115.64 μmol/L and 105.43±97.85 μmol/L 1 and 2 weeks after operation, respectively. No significant difference was found in the effect between PTBIED and PTIBS. Short-term complications developed in 33 patients. Seven patients died 30 days after operation.
CONCLUSION: Interventional therapy may be simple, safe and effective in the treatment of malignant obstructive jaundice.
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