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Non-alcoholic fatty liver disease: the problems we are facing |
ing-Tong Wang and Yu-Lan Liu |
Beijing, China
From the Department of Gastroenterology, People’s Hospital, Beijing University, Beijing 100044, China (Wang JT and Liu YL)
Correspondence: Jing-Tong Wang, MD, Department of Gastroenterology, People’s Hospital, Beijing University, Beijing 100044, China (Tel: 86-10-68314422ext5262; Fax: 86-10-68313836; Email: jingtongw@yahoo.com.cn) |
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Abstract OBJECTIVE: To review the current state of research in non-alcoholic fatty liver disease (NAFLD).
DATA RESOURCES: Searching Medline (1994-2002) and Chinese Medical Journals Index (1998- 2002) for articles on NAFLD.
RESULTS: NAFLD is a new and challenging field with increasing recognition although its pathogenesis is poorly understood. “Two hits” hypothesis is still the leading theory guiding current research.
CONCLUSIONS: Genetic study is a promising way that might lead to breakthrough in NAFLD research. NAFLD study in China is at an initial stage and there is a long way to go.
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