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Immune protection of auxiliary liver to other allograft: report of 3 cases |
Nian-Qiao Gong and Qi-Fa Ye |
Wuhan, China
From the Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China (Gong NQ and Ye QF)
Correspondence: Nian-Qiao Gong, MD, Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China (Tel: 86-27-83663409; Fax: 86-27-8380 8080; Email: nqgong@tjh.tjmu.edu.cn) |
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Abstract OBJECTIVE: To assess the immune status of auxiliary liver transplantation and to clarify the immune protection of auxiliary liver to other allograft.
METHODS: Immunological markers and pathological changes in 3 patients undergoing auxiliary liver transplantation were analysed.
RESULTS: The lower the concentration of immunosuppressive agent, the less the rejection and the milder the intensity in the 3 patients. The function of allograft after auxiliary liver transplantation was excellent.
CONCLUSIONS: Patients are in a low immune reaction state after auxiliary liver transplantation. Auxiliary liver can protect other allografts by related immunological mechanisms. The side-effects of low-concentration immunosuppressive agents on auxiliary liver and other allografts are mild.
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