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Molecular adsorbent recirculating system in dealing with maternal Amanita poisoning during the second pregnancy trimester: a case report |
Bang-Fu Wu and Min-Min Wang |
Guangzhou, China
Author Affiliations: Department of Gastroenterology, Guangzhou 12th Municipal People’s Hospital, Guangzhou 510620, China (Wu BF); and Therapeutic Blood Purification Research Center, University of Rostock, Germany (Wang MM)
Corresponding Author: Min-Min Wang, MD, Rm. 401, 555 East Zhongshan Rd. (2nd.), Bund Center, Shanghai 200010, China (Tel: 86-21-33020076; Fax: 86-21-33020076; Email: minminwang@yahoo.com.cn) |
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Abstract BACKGROUND: A 27-year-old woman in her 20th week of pregnancy was hospitalized because of food poisoning caused by Amanita phalloides.
METHODS: Previously extracorporeal purification treatments with 2 times of hemodialysis plus hemoperfusion and a high volume therapeutic plasma exchange (PE) in addition to intensive medication during the first 8 days failed to improve hepatic encephalopathy (HE) and liver function but developed deep coma with severe blood chemistry and signs of threatened abortion.
RESULTS: Treatments with intermittent molecular adsorbent recirculating system (MARS) for 3 times resulted in an immediate improvement of liver function and clinical symptoms including HE and threatened abortion until her fully recovery. When the life-threatening maternal illness was cured gestation went on until premature birth at the 36th week of pregnancy, and the infant underwent an undisturbed development.
CONCLUSION: MARS method appears to be an optimal therapy for patients with acute liver failure secondary to cytoxic mushroom poisoning during pregnancy.
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Cite this article: |
Wu BF,
Wang MM.
Molecular adsorbent recirculating system in dealing with maternal Amanita poisoning during the second pregnancy trimester: a case report.
Hepatobiliary Pancreat Dis Int
2004;
3(1):
152-154. DOI:
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URL: |
http://dx.doi.org/ OR http://www.hbpdint.com/EN/Y2004/V3/I1/152 |
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