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| 99Tcm-DISIDA hepatobiliary imaging in evaluating gallbladder function in patients with spinal cord injury |
| Chang-Suo Xia, Xuan-Ying Yang and Guang-Xiang Hong |
Qingdao, China
Author Affiliations: Department of Orthopaedics, Affiliated Hospital, Qingdao University Medical College, Qingdao 266003, China (Xia CS and Yang XY), and Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China (Hong GX)
Corresponding Author: Chang-Suo Xia, MD, Department of Orthopaedics, Affiliated Hospital, Qingdao University Medical College, Qingdao 266003, China (Tel: 86-532-82911276; Fax: 86-532- 82911276; Email: xcs009@163.com) |
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Abstract BACKGROUND: Spinal cord injury (SCI) is associated with increased prevalence of gallstones and acute acalculous cholecystitis. A possible explanation for the increased prevalence of gallstones in SCI patients is decreased gallbladder motility causing gallbladder stasis. In this study, we investigated gallbladder function in patients with SCI.
METHODS: Eighteen normal controls, 16 trauma controls and 46 SCI patients were included in this study. Gallbladder function was measured by technium 99m-labeled imino-diacetic acid analogue (99Tcm-DISIDA) hepatobiliary imaging and represented by filling fraction (FF) and ejection fraction (EF). The data from SCI patients were analyzed according to old versus young, female versus male, heavy versus light body weight, ASIA A & B versus ASIA C & D classification, high- versus low-level injury, and long versus short injury duration.
RESULTS: Fifty-two percent of SCI patients had abnormal FF and 59% had abnormal EF. Significantly decreased FF and EF values were found in SCI patients, especially in female patients with severe and high-level injuries.
CONCLUSION: Quantitative 99Tcm-DISIDA cholescinti-graphy showed that SCI can significantly impair gallbladder function.
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2007, Vol. 6 
