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| Isolated hepatosplenic tuberculosis |
| Vinay Kumar and Durgatosh Pandey |
Varanasi, India
Author Affiliations: Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India (Kumar V and Pandey D)
Corresponding Author: Durgatosh Pandey, MD, Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India (Tel: 91-542-2309511; Fax: 91-542- 2368856; Email: durgatosh@yahoo.co.in) |
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Abstract BACKGROUND: Tuberculosis rarely involves the liver and spleen and when it does so, it is usually associated with disseminated disease.
METHOD: We report a patient with isolated tuberculosis of the liver and spleen.
RESULTS: A 50-year-old man presented with weakness and loss of weight for two months. CT scan of the abdomen showed multiple small hypodense lesions in the liver and spleen. Image-guided biopsy of liver lesion was inconclusive as it showed normal hepatocytes with interspersed lymphocytes. On laparotomy, the liver and spleen were studded with multiple small nodules. A 5-cm wedge of the liver was resected. Histopathological examination confirmed the diagnosis of tubercular hepatitis. A detailed work-up failed to identify any other focus of tuberculosis.
CONCLUSION: Although rare, tuberculosis should also be considered in the differential diagnosis for multiple nodules in the liver and spleen, along with lymphoproliferative diseases and metastatic lesions.
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2008, Vol. 7 
