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| Biliary tract reconstruction using jejunal tube: an experimental study in dogs |
| Eliane Anrain Trentini, Eduardo Crema, Juan Carlos Llanos, Mauro Masson Lerco, Luiz Alberto Magna and Luiz Sergio Leonardi |
Campinas, SP, Brazil
Author Affiliations: State University of Campinas, Faculty of Medical Sciences, Department of Surgery (Trentini EA, Magna LA and Leonardi LS), Federal University of Triângulo Mineiro (Crema E) and São Paulo State University "Júlio de Mesquita Filho", Faculty of Medicine of Botucatu, Department of Surgery and Orthopedics (Llanos JC and Lerco MM), 17017-240-Bauru-SP-Brazil
Corresponding Author: Eliane Anrain Trentini, Rua Alfredo Fontão, 5-40-Apto. 113, Vila Samaritana, 17017-240-Bauru-SP-Brazil (Tel: +55-14-3227 3050/+55-14-9651 2816; Fax: +55-14-3321 3000; Email: eatrentini@uol.com.br) |
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Abstract BACKGROUND: To physiologically reconstruct the biliary tract, Crema et al suggested the application of the Monti principle to the biliary tract, already used in humans for the urinary tract. With this technique, a jejunal segment is transversely retubularized. This study aimed to evaluate the efficacy of jejunal tube interposition between the common bile duct and duodenum in dogs.
METHODS: Thirteen dogs underwent a laparoscopic common bile duct ligature, followed by a biliodigestive connection by jejunal tube interposition after one week. The levels of glutamic-pyruvic and glutamic-oxalacetic transaminases, total bilirubins, alkaline phosphatase and gamma-glutamyltransferase were assessed before surgery and thereafter weekly until euthanasia, which was performed 6 weeks after biliodigestive connection.
RESULTS: Data on 9 dogs were analyzed statistically. The dogs presented with obstructive jaundice after common bile duct ligature, as confirmed by biochemical examination. They showed a statistically significant reduction in cholestasis after biliodigestive connection by jejunal tube interposition and were healthy until the end of the experiment.
CONCLUSION: A statistically significant reduction was seen in total bilirubin and canalicular enzymes (alkaline phosphatase and gamma-glutamyltransferase) in the 9 dogs 6 weeks after biliodigestive connetion by jejunal tube interposition.
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2009, Vol. 8 
