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Long-term survival of a patient after resection of a gastrointestinal stromal tumor arising from the pancreas |
Filip Cecka, Bohumil Jon, Alexander Ferko, Zdenek Subrt, Dimitar H Nikolov and Vera Tycova |
Hradec Kralove, Czech Republic
Author Affiliations: Department of Surgery (Cecka F, Jon B, Ferko A and Subrt Z) and Fingerland Department of Pathology (Nikolov DH and Tycova V), Faculty of Medicine and University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic; Department of Field Surgery, Military Health Science Faculty, Hradec Kralove, Defence University Brno, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic (Ferko A and Subrt Z)
Corresponding Author: Filip Cecka, MD, Department of Surgery, Faculty of Medicine and University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic (Tel: ++420-737-163931; Fax: ++420-495- 832026, Email: filip.cecka@seznam.cz) |
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Abstract BACKGROUND: Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term follow-up of the patients.
METHOD: This report describes an interesting and unusual case of GIST arising from the pancreas.
RESULTS: A 74-year-old female presented with a palpable abdominal mass. CT scan showed a large mass 11×8×4 cm originating from the tail of the pancreas. Percutaneous biopsy revealed a GIST predominantly with spindle cells, but some parts also contained epitheloid cells. The patient was treated by distal pancreatic resection with splenectomy. Immunohistochemistry of the tumor showed a staining pattern characteristic of GIST. The patient has achieved a long-term survival of five years and six months without any sign of recurrence of the disease.
CONCLUSION: This is the first reported case of an extra-gastrointestinal stromal tumor arising from the pancreas treated surgically, with a long-term survival.
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