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High-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients awaiting liver transplantation |
Tan To Cheung, Kenneth SH Chok, Regina CL Lo, William W Sharr, See Ching Chan, Ronnie TP Poon, Sheung Tat Fan and Chung Mau Lo |
Hong Kong, China
Author Affiliations: Department of Surgery (Cheung TT, Chok KSH, Sharr WW, Chan SC, Poon RTP, Fan ST and Lo CM), Department of Pathology (Lo RCL), and State Key Laboratory for Liver Research (Chan SC, Poon RTP, Fan ST and Lo CM), The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China
Corresponding Author: Tan To Cheung, MBBS, Department of Surgery, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China (Tel: 852-22553025; Fax: 852-28165284; Email: tantocheung@hotmail.com) |
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Abstract The scarcity of liver grafts in Asia leads to a significant dropout of patients from liver transplant waiting lists, particularly patients with hepatocellular carcinoma and a low model for end-stage liver disease score. In order to reduce dropping out, different bridging therapies are employed. We report the use of high-intensity focused ultrasound ablation as a bridging therapy for a patient with hepatocellular carcinoma of stage two and an extremely low platelet count (20×109/L). The ablation was successful. Blood tests showed that his liver function was similar before and after the treatment. No adhesion was encountered in the liver transplantation performed six months later.
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