|
|
|
| Strategies for pancreatic anastomosis after pancreaticoduodenectomy: What really matters? |
| Jin Xu a,b,c,d, Shun-Rong Ji a,b,c,d, Bo Zhang a,b,c,d, Quan-Xing Ni a,b,c,d, Xian-Jun Yu a,b,c,d,∗ |
a Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
b Department of Oncology, Shanghai Medical College, Fudan Univeristy, Shanghai 200032, China
c Shanghai Pancreatic Cancer Institute, Shanghai 200032, China
d Pancreatic Cancer Institute, Fudan Univeristy, Shanghai 200032, China
∗ Corresponding author at: Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
E-mail address: yuxianjun@fudanpci.org (X.-J. Yu). |
|
|
|
Abstract Background: The postoperative pancreatic fistula rate remains approximately 10–20% even in institutions treating a high-volume of pancreatic cases. The best strategy to restore the continuity between the pancreatic remnant and the digestive tract is still in debate.
Data sources: Studies were identified by searching PubMed for studies published between January 1934 (when pancreaticogastrostomy was technically feasible) and December 2016. The following search terms were used: “duct-to-mucosa”, "invagination”, "pancreaticojejunostomy”, "pancreaticogastrostomy”, and “pancreaticoduodenectomy”. The search was limited to English publications.
Results: Many technical methods have been developed and optimized to restore pancreaticoenteric continuity, including pancreaticojejunostomy, pancreaticogastrostomy, and stented drainage of the pancreatic duct, among other modifications. Researchers have also attempted to decrease the postoperative pancreatic fistula after pancreaticoduodenectomy by using fibrin glue and somatostatin analogues. However, no significant decrease in postoperative pancreatic fistula has been observed in most of these studies, and only an external pancreatic duct stent has been found to decrease the leakage rate of pancreatic anastomosis after pancreaticojejunostomy.
Conclusion: Pancreatic surgeons should choose a suitable technique according to the characteristics of individual cases.
|
|
|
|
|
|
|
|
|
2018, Vol. 17 
