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| Helicobacter pylori and portal hypertensive gastropathy |
| Ji-Ke Hu a , Xue-Mei Li a , Bao-Hong Gu a , Fan Zhang a , Yu-Min Li b , Hao Chen b , c , ∗ |
a The Second Clinical Medical College of Lanzhou University, Lanzhou 730000, China
b The Key Laboratory of the Digestive System Tumors of Gansu Province, Second Hospital of Lanzhou University, Lanzhou 730000, China
c The Department of Tumor Surgery, Second Hospital of Lanzhou University, Lanzhou 730000, China
∗ Corresponding author at: Department of Tumor Surgery, Second Hospital of Lanzhou University, Lanzhou 730 0 0 0, China.
E-mail address: chenhaodrs@163.com (H. Chen). |
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Abstract H. pylori lives in the gastric epithelial cells, sometimes in gastric glands. Whether or not the proliferation and biological behavior of H. pylori can be influenced by the status of the gastric mucosa is still unknown. Portal hypertensive gastropathy (PHG) is a blood drainage obstructive disease. In this pathologic environment, gastric mucosa may be further impaired when patients are infected with H. pylori . The role of H. pylori in the pathogenesis of PHG and the effect of PHG on H. pylori infection is poorly defined and controversial. We wonder whether H. pylori or its products can migrate to distant organ after anatomical changes of gastric mucosa by PHG.
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2018, Vol. 17 
