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Donor ductal anomaly is not a contraindication to right liver lobe donation ? |
Kenneth SH Chok a , b , ∗, James YY Fung b , c , Wing Chiu Dai a , Sui Ling Sin a , Ka Wing Ma a , Albert CY Chan a , b , Tan To Cheung a , b , Chung Mau Lo a , b |
a Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China
b State Key Laboratory for Liver Research, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China
c Department of Medicine, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China
? The paper was presented at the 12th Academic Surgical Congress on February 7–9, 2017 at Las Vegas, USA.
∗ Corresponding author at: Department of Surgery, The University of Hong Kong,
102 Pok Fu Lam Road, Hong Kong, China.
E-mail address: kennethchok@gmail.com (K.S. Chok). |
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Abstract Background: Data of living-donor liver transplantation (LDLT) suggested that donor ductal anomaly may contribute to postoperative biliary complications in recipients and in donors. This retrospective study aimed to determine if the occurrence of postoperative biliary stricture in donors or recipients in right-lobe LDLT (RLDLT) is related to donor biliary anatomy type.
Methods: We analyzed our RLDLT recipients’ clinical data and those of their graft donors. The recipients were divided into 2 groups: with and without postoperative biliary stricture. The 2 groups were compared. The primary endpoints were donor biliary anatomy type and postoperative biliary complication incidence; the secondary endpoints were 1-, 3- and 5-year graft and patient survival rates.
Results: Totally 127 patients were included in the study; 25 (19.7%) of them developed biliary anastomotic stricture. In these 25 patients, 16 had type A biliary anatomy, 3 had type B, 2 had type C, 3 had type D, and 1 had type E. In the 127 donors, 96 (75.6%) had type A biliary anatomy, 13 (10.2%) had type B, 6 (4.7%) had type C, 10 (7.9%) had type D, and 2 (1.6%) had type E. Biliary stricture was seen in 2 donors, who had type A biliary anatomy. None of the recipients or donors developed bile leakage. No association between the occurrence of postoperative biliary stricture and donor biliary anatomy type was found ( P = 0.527).
Conclusions: The incidence of biliary stricture in donors or recipients after RLDLT was not related to donor biliary anatomy type. As postoperative complications were similar in whatever type of donor bile duct anatomy, donor ductal anomaly should not be considered a contraindication to donation of right liver lobe.
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