Liver transplantation for intrahepatic and perihilar cholangiocarcinoma: Current and future

doi:10.1016/j.hbpd.2020.02.008

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Abstract Cholangiocarcinomas are categorized as intrahepatic cholangiocarcinoma (iCCA), perihilar cholangiocarcinoma (pCCA), and distal cholangiocarcinoma (dCCA) [1]. iCCA and pCCA are the second most common primary hepatobiliary malignant neoplasms [1,2]. Most patients with iCCA and pCCA have asymptomatic clinical course, highly aggressive nature and dismal prognosis [3]. Complete surgical resection offers the best possibility of long-term survival but only a minority of patients are amenable to R0 resection [4]. Tumor involvement of segmental bilateral intrahepatic bile duct, inadequate remnant liver volume or hepatic functional reserve due to underlying chronic liver disease, are key factors limiting the resectability of iCCA and pCCA. Liver transplantation (LT) provides an option for patients with unresectable iCCA and pCCA [4].

Key words： Liver transplantation Intrahepatic cholangiocarcinoma Perihilar cholangiocarcinoma

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	Zheng SS
	Yang Z
	Wu YC

Cite this article:

Zheng SS, Yang Z, Wu YC. Liver transplantation for intrahepatic and perihilar cholangiocarcinoma: Current and future. Hepatobiliary Pancreat Dis Int 2020; 19(2): 101-102. DOI:10.1016/j.hbpd.2020.02.008

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http://dx.doi.org/10.1016/j.hbpd.2020.02.008 OR http://www.hbpdint.com/EN/Y2020/V19/I2/101