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Rare giant asymptomatic skull metastasis from intrahepatic cholangiocarcinoma |
Man-Tao Chen a , Yong-Qing Zhou a , Tian-Ya Wu b , De-Xin Cheng a , Gu Li a , Ren-Ya Zhan a , ∗ |
a Department of Neurosurgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
b Department of Neurosurgery, Zhuji People’s Hospital of Zhejiang Province, Zhuji 311800, China
∗ Corresponding author.
E-mail address: 1196057@zju.edu.cn (R.-Y. Zhan). |
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Abstract Skull metastases are common cranial tumors in adults. Breast cancer, lung cancer, prostate cancer and malignant lymphoma are the most common types of primary tumor. Skull metastases are often asymptomatic; however, they can also cause local pain and cranial nerve palsies, and even severe disability due to compression of the dural sinuses [1] . In these cases, surgery is necessary to improve the patients’ quality of life, especially relieving the mass effect of skull metastasis. Skull metastases from less common malignant tumors such as intrahepatic cholangiocarcinoma (ICC) have rarely been described [2–6] , and its treatment still remained a big challenge for all neurosurgeons. Here, we present an asymptomatic case of giant skull metastases from ICC treated with complete resection and chemotherapy.
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