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Recent evolution of living donor liver transplantation at Kyoto University: How to achieve a one-year overall survival rate of 99%? |
Toshimi Kaido a , b |
a Department of Gastroenterological and General Surgery, St. Luke’s International University Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, Japan
b Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
E-mail address: kaido@kuhp.kyoto-u.ac.jp |
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Abstract Previously, living donor liver transplantation was considered as a “high-risk, high-return”medical treat- ment due to the relatively high short-term mortality. It is our task to change “high-risk, high-return”into a “low-risk, high-return”situation. In this review article, the recent evolutions in living donor liver transplantation for both donors and recipients at Kyoto University such as portal vein pressure modulation, hybrid donor operation, and perioperative management considering sarcopenia, focusing on improvement of short-term outcomes are described. Under a paradigm of “marketing and innovation”, various innovations and efforts have been made over the last decade aiming at improving the short-term outcomes of both donors and recipients. By doing so, excellent short-term results after living donor liver transplantation have been achieved, along with a potentially epoch-making discoveries.
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