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| Simplified calculation of bile cholesterol saturation index |
| Fen-Ming Zhang, Xin Jiang, Sha Li, Long-Gui Ning, Fang-Fang Guo, Guo-Qiang Xu ∗ |
Department of Gastroenterology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
∗ Corresponding author.
E-mail address: xugq@zju.edu.cn (G.-Q. Xu). |
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Abstract Gallstones (cholelithiasis) are masses in the gallbladder or biliary tract that are caused by abnormally high levels of either cholesterol or bilirubin in bile [1]. It is a multifactorial disease and the main pathogenesis is the increased secretion of bile cholesterol, which can increase the cholesterol saturation index (CSI) of bile. Patients with CSI greater than 1 are more likely to develop gallstones. Bile is a kind of dark green to yellowish-brown liquid containing > 90% water. Cholesterol, lecithin and bile salts are the three main lipid species in bile and combined to form the main components of gallstones [1].
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2022, Vol. 21 
