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| Modern technology, liver surgery and transplantation |
| Jan Lerut |
Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Avenue Hippocrate 55 1200, Brussels, Belgium
E-mail address: jan.lerut@saintluc.uclouvain.be |
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Abstract Since the first right hepatectomy performed by Jean-Louis Lortat-Jacob on October 16, 1951 and the first liver transplantation by Thomas Earl Starzl on March 1, 1963, hepatobiliary surgery and liver transplantation had a spectacular development [1,2 ]. After the hesitating beginning in the 1950’s and 1960’s, their evolution really took off in the 1980’, reaching high-speed velocity in the 21st century. Improved knowledge of the (surgical) anatomy, refinement of techniques together with better insights into the (regenerative) physiopathology of the liver led to the development not only of precise surgical techniques but also to carefully-thought surgical strategies combining locoregional and systemic therapies [3–9]. Indeed, a multidisciplinary approach allowed to broaden the access of many patients to a curative treatment. Partial or total hepatectomy after downstaging and/or volume enhancing procedures using advanced locoregional and/or systemic therapies allowed to develop the concepts of two-stage hepatectomy, Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS), Intra-Operative UltraSonography-guided (IOUS) parenchymal sparing hepatectomy and liver resection using in-situ cooling as well as reduced-size, split, Resection And Partial liver transplantation with Delayed hepatectomy (RAPID) and living donor liver transplantation (LDLT) [2,9-16 ].
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2022, Vol. 21 
