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Predictive value of lipocalin 2 and cystatin C for acute kidney injury in patients with cirrhosis |
Xue-Qing Ma a , Si-Si Yang b , Huan-Qiu Wang b , Jie Wu b , Cheng-Bo Yu b , ∗ |
a Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China
b The First Affiliated Hospital, Zhejiang University School of Medicine, Key Laboratory for Diagnosis and Treatment of Infectious Disease, 79 Qingchun Road, Hangzhou 310003, China
∗ Corresponding author.
E-mail address: yuchengbo1974@mail.zju.edu.cn (C.-B. Yu) . |
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Abstract Acute kidney injury (AKI) is a common complication in patients with liver cirrhosis and with a high mortality [1]; early diagnosis and treatment improve survival. Lipocalin 2 (NGAL) and cystatin C have been identified as early biomarkers of AKI. However, controversy remains regarding the utility of NGAL and cystatin C for the early diagnosis of AKI in patients with liver cirrhosis. This study aimed to evaluate the performance of NGAL and cystatin C in diagnosing AKI in patients with liver cirrhosis and predicting their clinical outcomes.
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