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| Current controversies and challenges for resection of pancreatic ductal adenocarcinoma in pancreatic head aiming at cure |
| Wan Yee Lau |
Faculty of Medicine, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
E-mail address: josephlau@cuhk.edu.hk |
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Abstract Pancreatic ductal adenocarcinoma (PDAC) is a very common but a highly lethal malignancy due to its biological aggressive behavior. PDAC more commonly affects the head than other parts of the pancreas. As PDAC in the head of pancreas is located at an anatomical position with a lot of adjacent vital structures, and the cornerstone of treatment aiming at cure is pancreaticoduodenectomy (PD), only about 20% of patients have resectable disease at the time of clinical presentation [1], with a very low 5-year overall survival of around 20% after surgical resection with curative intent [2].
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2023, Vol. 22 
