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Conversion surgery for pancreatic cancer: A future paradigm also for stage IV tumors? |
Thilo Hackert |
Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Martinistraße 52, Hamburg 20246, Germany
E-mail address: t.hackert@uke.de |
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Abstract Pancreatic ductal adenocarcinoma (PDAC) remains still one of the most lethal tumor entities and will be the second leading cause of cancer-related death within the next ten years for both male and female patients. This frustrating development is mainly explained by an increasing incidence and still limited therapeutical success [1,2]. Only about 15%-20% of all patients diagnosed with PDAC qualify for upfront surgery, while in the remaining patients, locally advanced or metastatic tumor stages are found at diagnosis, the largest proportion of these patients presenting with stage IV tumors [3].
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