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| Transcatheter arterial chemoembolization after percutaneous microwave ablation and portal vein embolization for advanced hepatocellular carcinoma |
| Jian Cheng a , De-Fei Hong b , Cheng-Wu Zhang a , Xiao-Ming Fan a , Zu-Yan Luo a , Wei-Feng Yao a , Li-Ming Jin a , ∗ |
a General Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital of Hangzhou Medical College, Hangzhou 310014, China
b Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310020, China
∗ Corresponding author.
E-mail address: hz_jlm@163.com (L.-M. Jin). |
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Abstract Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) promotes the future liver remnant (FLR) rapid proliferation in the short term, which in turn provides an opportunity for radical surgical resection to hepatocellular carcinoma (HCC) for patients with insufficient FLR [1,2]. However, the HCC patients with cirrhosis have slow compensatory hyperplasia of the FLR, and hence, some patients cannot tolerate second-stage hepatectomy due to insufficient growth of FLR or liver dysfunction after first-stage ALPPS [3]. The perioperative mortality and complication rates of traditional ALPPS are high [4]. Conversely, percutaneous microwave ablation liver partition and portal vein embolization (PALPP) avoids the first step of abdominal surgery with low risk and is minimally invasive [5]. It provides a safe opportunity of secondary salvage treatment for HCC patients who cannot tolerate second-stage hepatectomy because of insufficient compensatory hyperplasia of FLR or severe cirrhosis. In this study, we presented the clinical data of transcatheter arterial chemoembolization (TACE) combined with PALPP in a patient with advanced HCC and cirrhosis and assessed the clinical effect over a 47-month follow-up.
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2023, Vol. 22 
