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Regression of recurrent granulosa cell tumor liver metastases following selective internal radiation therapy |
Omar A Mownah a , ∗, John D Leahy a , Jeffrey Summers b , Stephen M Gregory a , Nigel D Heaton a |
a Institute of Liver Studies, King’s Healthcare Partners, King’s College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK
b Department of Oncology, Maidstone and Tunbridge Wells NHS Trust, Maidstone ME16 9QQ, UK
∗ Corresponding author.
E-mail address: omar.mownah@nhs.net (O.A. Mownah). |
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Abstract Granulosa cell tumor (GCT) is the most common sex cordstromal tumor, comprising 5% of all ovarian malignancies [1]. The disease course is indolent, and the majority of cases present at stage 1. However, metastases may develop with potential sites being peritoneum, lung, brain, liver and bone [2]. Due to the rarity of the disease, published evidence for management of granulosa cell tumor liver metastases (GCTLM) is limited. Surgical resection is the optimal treatment in instances where there is a high chance of achieving complete resection [3]. With regards to unresectable GCTLM there is a paucity of evidence to guide treatment strategy.
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