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Tri-modal death distribution towards personalized management of intraductal papillary neoplasm of the bile duct patients: Every story has its own conclusion |
Vor Luvira |
Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
E-mail address: vor@kku.ac.th
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Abstract The concept of intraductal papillary neoplasm of the bile duct (IPNB) has gained recognition as a discrete entity [1,2], possessing many features including multiplicity [3,4], mucin production [3], slow progression [3,5], various morphology [6,7], easy sloughing and seeding [8], and having unique risk factors [2,9-11]. We have previously proposed a morphologic classification [6] and a progression model of IPNB [12], aiming to facilitate comprehension of the underlying characteristics of IPNB, thereby enabling the development of tailored treatment plans for individual patients. Despite the numerous advancements in IPNB research, the improvement of treatment outcomes for these patients has been limited due to the significant heterogeneity shown in this condition. There is no universally applicable policy that can cater to the needs of all individuals.
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