Severe and delayed immune-mediated hemolysis post-liver transplantation
Quan Zhuang, Hong Liu, Ke Cheng, Ying Niu, Xing-Guo She and Ying-Zi Ming
Transplantation Center of the Third Xiangya Hospital, Central South University, Changsha 410013, China (Zhuang Q, Liu H, Cheng K, Niu Y, She XG and Ming YZ)
Corresponding Author: Ying-Zi Ming
(Email: myz_china@aliyun.com)
Abstract：To the Editor:
Hemolysis, which is caused by a variety of immune and non-immune mechanisms, is a well-recognized complication of solid organ transplantation.[1] Hemolysis post-liver transplantation can be induced by drug, infection, autoimmune disorders, blood-group incompatible transplantation or passenger lymphocyte syndrome (PLS), which mostly is a quick and non-fatal complication and usually recovered easily. However, immune-mediated hemolysis post-liver transplantation is rare. The antibodies can be of donor and/or recipient origin.[2] Recently, we encountered a case of severe and delayed hemolysis post-liver transplantation caused by anti-e autoantibody. It did not response by all the regular treatments. In addition to ABO and Rh blood systems, there are also some other blood systems in human beings, such as Lewis, MNSs or Kell blood groups.[3] Although those irregular blood phenotypes are not regularly tested, we still need understand comprehensively.
. [J]. Hepatobiliary Pancreat Dis Int, 2017, 16(6): 665-668.
Zhuang Q, Liu H, Cheng K, Niu Y, She XG, Ming YZ. Severe and delayed immune-mediated hemolysis post-liver transplantation. Hepatobiliary Pancreat Dis Int, 2017, 16(6): 665-668.
2017, Vol. 16 
