Artificial liver support molecular adsorbents recirculating system therapy as a bridge to re-transplantation in two cases of long anhepatic duration
Yi-He Liu, Yu Wang, Li-Xin Yu, Li-Ying Sun, Bao-Lan Feng, Zhong-Yang Shen and Min-Min Wang
Tianjin, China
Author Affiliations: Tianjin Organ Transplantation Institute, Tianjin First Central Hospital, Tianjin 300192, China (Liu YH, Wang Y, Yu LX, Sun LY, Feng BL and Shen ZY); Therapeutic Blood Purification Research Center, University of Rostock, Germany (Wang MM) Corresponding Author: Min-Min Wang, MD, Room 401, 555 East Zhongshan Rd. (2nd.), Bund Center, Shanghai 200010, China (Tel: 86-21-33020076; Fax: 86-21-33020076; Email: minminwang@yahoo.com.cn)
BACKGROUND: Molecular adsorbents recirculating system (MARS) liver support therapy is the development of albumin dialysis. This study was to assess the successful application of MARS artificial liver support therapy as a bridge to re-transplantation in two cases of long anhepatic duration.
METHODS: MARS therapy was given after failure plasma-exchange (PE) treatment, which resulted in circulatory derangement and acute renal dysfunction in a 36-year-old male patient. Finally his uncontrolled anhepatic condition led to a successful re-transplantation. In another 48-year-old man who was diagnosed as having primary nonfunction (PNF) during the liver transplantation, 10-hour MARS treatment contributed to smooth bridging of his anhepatic phase.
RESULTS: The two anhepatic patients were bridged for 26 and 17 hours respectively to re-transplantation with MARS therapy.
CONCLUSION: Our experience proves that MARS artificial liver can be an effective support for long time bridging PNF until re-transplantation is available.
. [J]. Hepatobiliary Pancreat Dis Int, 2004, 3(2): 316-316.
Liu YH, Wang Y, Yu LX, Sun LY, Feng BL, Shen ZY, Wang MM. Artificial liver support molecular adsorbents recirculating system therapy as a bridge to re-transplantation in two cases of long anhepatic duration. Hepatobiliary Pancreat Dis Int, 2004, 3(2): 316-316.
2004, Vol. 3 
